Article

Anti-inflammatory immunomodulation for the treatment of Congenital Diaphragmatic Hernia

2023-11-09

Abstract excerpt

Congenital diaphragmatic hernia (CDH) is a rare disease where the diaphragm does not develop properly altering lung development with no established therapy. We have analyzed the effect of anti-inflammatory immunomodulators that influence macrophage activation in animal CDH models. In the widely-used nitrofen-induced model of CDH in pregnant rats, administration of a single dose of atypical Toll-like Receptors TLR2...

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Literature Corpus work: 60380372-18c9-5907-9968-7c8005712c18
DOI: 10.1101/2023.11.07.565809

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