Article

Development and Clinical Validation of a Skin Test for In Vivo Assessment of SARS-CoV-2 Specific T-Cell Immunity

2025-08-11

Abstract excerpt

A novel skin test for in vivo assessment of SARS CoV 2 specific T cell immunity was developed using CoronaDerm PS, a multi epitope recombinant polypeptide encompassing MHC II–binding CD4+ T cell epitopes of the SARS CoV 2 structural proteins (S, E, M) and full length nucleocapsid (N). In silico epitope prediction and modeling guided antigen design, which was expressed in E. coli, purified (>95% purity), and for...

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Literature Corpus work: 602c2318-e30d-5c3e-820f-15563af655d2
DOI: 10.20944/preprints202508.0493.v1

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