Article

Modern Pharmacologic Management of Rheumatoid Arthritis: From Methotrexate to Targeted Therapies

2025-12-16

Abstract excerpt

Rheumatoid arthritis (RA) is a chronic, systemic autoimmune pathology characterized by symmetric synovitis, pannus formation, and the potential for severe extra-articular manifestations. Despite historical associations with high morbidity, the 'treat-to-target' strategy has revolutionized patient outcomes. This review analyzes the pharmacological evolution of RA management over the last decade. We examine the foun...

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Literature Corpus work: 5fd02716-f1aa-5661-a06c-8800277e646e
DOI: 10.20944/preprints202512.1464.v1

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