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Genetic incompatibility combined with female-lethality is effective and robust in simulations of <i>Aedes aegypti</i> population control

2018-05-07

Abstract excerpt

Recent reports of CRISPR/Cas9-based suppression gene drives in insects underscore the challenge of overcoming genetic resistance. Here we present results from agent-based simulation modeling of a novel Field-Amplified Male Sterility System (FAMSS) that outperforms suppression gene drives when challenged with genetic resistance. FAMSS combines a recently described synthetic genetic incompatibility approach with pre...

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Literature Corpus work
5f6f065e-70ac-5b22-bcac-62c0ca23693c
DOI
10.1101/316406
Open publication

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