Targeting sex determination to suppress mosquito populations

Abstract excerpt

Each year, hundreds of millions of people are infected with arboviruses such as dengue, yellow fever, chikungunya, and Zika, which are all primarily spread by the notorious mosquito Aedes aegypti . Traditional control measures have proven insufficient, necessitating innovations. In response, here we generate a next-generation CRISPR-based precision-guided sterile insect technique (pgSIT) for Ae. aegypti that disru...

Topics

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• CRISPR and Genetic Engineering
• Insect symbiosis and bacterial influences
• Mosquito-borne diseases and control

Identifiers and source

Literature Corpus work

26d1b2b3-391d-56ef-bdbf-aad64abe643b

DOI

10.7554/elife.90199.3