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Glycogen synthase kinase 3 inhibition enhances mineral nodule formation by cementoblasts in vitro

2022-05-13

Abstract excerpt

<h4>Objectives: </h4> This study aimed to investigate whether GSK-3 inhibition (CHIR99021) effectively promoted mineralization by cementoblasts (OCCM-30).Materials and MethodsOCCM-30 cells were used and treated with different concentrations of CHIR99021 (2.5, 5 and 10 µM). Experiments included proliferation and viability, cellular metabolic activity, gene expression and mineral nodule formation by Xylene Orange at...

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Literature Corpus work
5f56eabe-f936-5e7e-843e-2fe42187c322
DOI
10.21203/rs.3.rs-1609594/v1
Open publication

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