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Down-regulation of A Human Herpesvirus 1 (HHV-1) MicroRNA in Infected Cells by Goniothalamin Treatment

2021-06-04

Abstract excerpt

Goniothalamin (GTN) has been proven to cause cell cycle arrest and apoptosis in human herpesvirus 1 (HHV-1) infected cells, but interestingly our preliminary transcriptomic analysis revealed other possible modes of action. The data showed that GTN treatment of HHV-1 clinical strain infected cells induced expression of the KLHL24 gene that encodes the Kelch-like 24 protein (KLHL24), a transcriptional inhibitor of...

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Literature Corpus work
5f49eccd-fb34-5953-908b-e127f6d90896
DOI
10.1101/2021.06.03.447015
Open publication

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