Article

Oxidative stress, cellular senescence and ageing

2016-01-01

Abstract excerpt

Almost a half century ago, the free radical theory of ageing proposed that the reactive oxygen species (ROS) is a key component which contributes to the pathophysiology of ageing in mammalian cells. Over the years, numerous studies have documented the role of oxidative stress caused by ROS in the ageing process of higher organisms. In particular, several age-associated disease models suggest that ROS and oxidative...

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Literature Corpus work: 5f104c11-313a-5db1-a00a-7ba99b5cfa6a
DOI: 10.3934/molsci.2016.3.300

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