Article

Non-invasive full quantification of dynamic [11C]PBR28 PET imaging with ASTRA

2026-03-03

Abstract excerpt

<title>Abstract</title> <p>Quantitative analysis of dynamic PET imaging requires metabolite-corrected arterial input functions, traditionally obtained through invasive arterial sampling. This limits broader adoption of fully quantitative kinetic modelling, particularly for tracers such as [11C]PBR28 that generate radiometabolites. Here we demonstrate that metabolite-corrected input functions can be estimated from...

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Literature Corpus work: 5eb2bd7c-522d-5f59-abf6-3396256c83f8
DOI: 10.21203/rs.3.rs-8895728/v1

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