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Article

Centromere Detection of Human Metaphase Chromosome Images using a Candidate Based Method

2015-11-18

Abstract excerpt

Accurate detection of the human metaphase chromosome centromere is an critical element of cytogenetic diagnostic techniques, including chromosome enumeration, karyotyping and radiation biodosimetry. Existing image processing methods can perform poorly in the presence of irregular boundaries, shape variations and premature sister chromatid separation, which can adversely affect centromere localization. We present a...

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Identifiers and source

Literature Corpus work
5e494bbd-1921-5119-a330-10b91da7a1ef
DOI
10.1101/032110
Open publication

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