Article

Functional annotation of rare structural variation in the human brain

2019-07-23

Abstract excerpt

Structural variants (SVs) contribute substantially to risk of many brain related disorders including autism and schizophrenia. However, annotating the potential contribution of SVs to disease remains a major challenge. Here, we integrated high resolution SV calling from genome-sequencing in 755 human post-mortem brains with dorsal lateral prefrontal cortex RNA-sequencing from a subset of 629 samples to quantify th...

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Literature Corpus work: 5e068561-4b6a-5d78-aa1f-b31150cca9ab
DOI: 10.1101/711754

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