Article

Deciphering the Non-Coding Genome in Autism Spectrum Disorders (ASD): A Study of De Novo and Rare Inherited Variants through Targeted Sequencing in Regulatory Regions

2024-10-15

Abstract excerpt

<h4>ABSTRACT</h4> ASD (Autism Spectrum Disorders) are NDDs (Neurodevelopmental Disorders) with complex etiology including multiple genetic and environmental factors. Non-coding mutations contribute to the multifactorial etiology of ASD by influencing gene activity through various regulatory mechanisms. Advances in genomic technologies, such as whole-genome sequencing (WGS) and chromatin interaction studies, have h...

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Literature Corpus work: ff56215a-e528-59bf-8f87-19ebc0ab2687
DOI: 10.1101/2024.10.14.24315434

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