Article

Analgesia by Cryotherapy in Patients with Chronic Pain with Analysis of Pain-Modulating and Pro-Inflammatory Parameters

2025-09-16

Abstract excerpt

<h4>Background: </h4> /Objectives: Whole-body cryotherapy (WBC) is increasingly utilized as a physical modality for managing chronic pain, although its mechanism of action remains incompletely understood. This study evaluated whether WBC influences serum levels of substance P, calprotectin, β-nerve growth factor (β-NGF), and calcitonin gene-related peptide (CGRP), which are implicated in pain modulation. <h4>Metho...

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Literature Corpus work: 5e015ba6-384a-54e1-bb6b-05fc24dd5ec1
DOI: 10.20944/preprints202509.1291.v1

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