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Intraoperative abobotulinumtoxinA alleviates pain after surgery and improves general wellness in a translational animal model

2022-04-11

Abstract excerpt

Pain after surgery remains a significant healthcare challenge. Here, activity of abobotulinumtoxinA (aboBoNT-A, Dysport ® ) was assessed in a post-surgical pain model in pigs. Full-skin-muscle incision and retraction surgery on the lower flank was followed by intradermal injections of either aboBoNT-A (100, 200, or 400 U/pig), vehicle (saline), or wound infiltration of liposomal extended-release bupivacaine. Anima...

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Literature Corpus work
4d5e86bf-fce7-54a3-8fbd-9b7c3a20ab50
DOI
10.21203/rs.3.rs-1519078/v1
Open publication

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Intraoperative abobotulinumtoxinA alleviates pain after surgery and improves general wellness in a translational animal modelDOI 10.21203/rs.3.rs-1519078/v1
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