Article

Exosomal MMP-1 transfers metastasis potential in triple-negative breast cancer through PAR1-mediated EMT

2021-08-10

Abstract excerpt

<title>Abstract</title> <p>Purpose Triple-negative breast cancer (TNBC) is a subtype of breast cancer with high risk of distant metastasis, in which the intercellular communication between tumor cells also plays a role. Exosomes can be released by tumor cells and promote distant metastasis through intercellular communication or changes in tumor microenvironment, it is an optimized transportation facility for bio...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5d75b18e-b6e4-55cb-a58c-a1056b4d5c4e
DOI: 10.21203/rs.3.rs-751066/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Exosomal MMP-1 transfers metastasis potential in triple-negative breast cancer through PAR1-mediated EMTDOI 10.21203/rs.3.rs-751066/v1Read

Multidimensional analysis to elucidate the possible mechanism of bone metastasis in breast cancerSemantic proximity Read

The role of EMT-related lncRNA in the process of triple-negative breast cancer metastasisSemantic proximity Read

Exosomal ANGPTL1 Attenuates Colorectal Cancer Liver Metastasis by Regulating Kupffer Cell Secretion Pattern and Impeding MMP9 Induced Vascular LeakinessSemantic proximity Read

MT1-MMP as a Key Regulator of MetastasisSemantic proximity Read

Updates on mechanistic insights and targeting of tumour metastasisSemantic proximity Read

Upregulation of MMPs in Metastatic Cascade of Breast Cancer To BrainSemantic proximity Read

Recent advances in understanding the complexities of metastasisSemantic proximity Read

From Cell Lines to Patients: Dissecting the Proteomic Landscape of Exosomes at Breast CancerSemantic proximity Read

LRP11-AS1 Promotes the Malignant Behavior of Triple Negative Breast Cancer Cells via the MiR-149-3p/NRP2 AxisSemantic proximity Read

Altered Expression of Secreted Mediator Genes That Mediate Aggressive Breast Cancer Metastasis to Distant OrgansSemantic proximity Read

Breast cancer derived exosomes promoted angiogenesis of endothelial cells in microenvironment via circHIPK3/miR-124-3p/MTDH axisSemantic proximity Read

Tumor cell-secreted soluble uPAR functions as a neutrophil chemoattractant to promote triple-negative breast cancer metastasisSemantic proximity Read