Article

Alpha-Gal Syndrome and the Gastrointestinal Tract: Epidemiology, Clinical Phenotype, Diagnosis, Management, and the Case for a Public Health Response

2026-06-26

Abstract excerpt

<h4>Background: </h4> /Objectives: Alpha-gal syndrome (AGS) is a tick-induced, IgE-mediated hypersensitivity to the oligosaccharide galactose-α-1,3-galactose (α-gal), which is expressed on glycoproteins and glycolipids of non-primate mammals but absent in humans. Gastrointestinal (GI) symptoms dominate the clinical presentation in a substantial proportion of patients yet remain systematically under-recognized, fre...

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Literature Corpus work: 5d61d74f-134f-53cf-b16f-d94d9d77d28a
DOI: 10.20944/preprints202606.0929.v1

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