Article

Germline stem cell isolation, lineage tracing, and aging in a protochordate

2025-09-02

Abstract excerpt

Germline stem cells (GSCs), the source of gametes, are the only stem cells capable of passing genes to future generations and are therefore considered units of natural selection. Yet, the factors that influence GSC fitness, and thus govern GSC competition, which exist in both protochordates and mammals, remain poorly understood. We studied how aging affects GSC fitness in the protochordate Botryllus schlosseri ,...

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Literature Corpus work: 5d607466-2ab9-5e01-acef-1f7fe4327357
DOI: 10.1101/2025.08.31.673173

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