Article

Novel miR-15b-5p/BTG2 regulatory axis drives esophageal cancer progression through multi-omics analysis and functional validation

2025-09-09

Abstract excerpt

<title>Abstract</title> <p>Background Esophageal cancer (EC), a leading cause of cancer-related mortality, lacks reliable biomarkers for early detection and prognosis. Dysregulated microRNAs (miRNAs) are emerging as pivotal regulators of tumor progression, but their context-specific roles and interactions with target genes in EC remain underexplored. Methods Multi-omics data from TCGA-ESCA and GEO datasets were i...

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Literature Corpus work: 5d25bc08-2fae-54a1-92c1-0731b1668628
DOI: 10.21203/rs.3.rs-6777740/v1

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