ALOX15 may function as a tumor biomarker, transitioning from pan-cancer comprehensive analysis to validation within head and heck squamous cell carcinoma

Abstract excerpt

<title>Abstract</title> <p>Arachidonate 15-Lipoxygenase (ALOX15) has been implicated in cellular homeostasis, yet its pan-cancer expression patterns, clinical relevance, and molecular mechanisms remain incompletely characterized. This study comprehensively analyzed ALOX15 expression across 33 cancer types using multi-omics data to evaluate its role in tumor progression, diagnostic potential, and therapeutic impli...

Topics

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• 2',5'-Oligoadenylate Synthetase
• Apoptosis
• Biomarkers, Tumor
• Epigenetics and DNA Methylation
• Ferroptosis and cancer prognosis
• Gene Expression Profiling
• Gene Expression Regulation, Neoplastic
• Ubiquitin and proteasome pathways

Identifiers and source

Literature Corpus work

2cc48012-eea8-5cc6-a035-6caaa2b73295

DOI

10.21203/rs.3.rs-8300114/v1