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Insulin Does Not Augment <i>In Vitro</i> Tumor Growth Under A Hyperglycemia-Mimicking Milieu And In A Calorie Restriction-Resembling Manner

2017-07-28

Abstract excerpt

<h4>Background</h4> Whether insulin enhances or represses tumor cell proliferation remains debating and inconclusive although epidemiological data indicated insulin use raises a risk of cancer incidence in patients with diabetes mellitus (DM). <h4>Methodology/Principle Findings</h4> We cultured rat pituitary adenoma cells in a high-glucose medium to simulate hyperglycemia occurring in DM patients. Upon incubatio...

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Literature Corpus work: 5d138715-70d4-5b23-958c-ea3822d5e1f9
DOI: 10.1101/169664

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