Article

Potent programmable antiviral against dengue virus in primary human cells by Cas13b RNP with short spacer and delivery by virus-like particle

2020-05-17

Abstract excerpt

<h4>Summary</h4> With sequencing as a standard frontline protocol to identify emerging viruses such zika virus and SARS-CoV2, direct utilization of sequence data to program antivirals against the viruses could accelerate drug development to treat their infections. CRISPR-Cas effectors are promising candidates that could be programmed to inactivate viral genetic material based on sequence data but several challeng...

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Literature Corpus work: 5c27845c-36c1-5333-b6db-6a4a8c9a62ba
DOI: 10.1101/2020.05.17.100388

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