Article

Discovery of therapeutic agents targeting <i>PKLR</i> for NAFLD using drug repositioning

2022-02-17

Abstract excerpt

<h4>Background & Aims</h4> Non-alcoholic fatty liver disease (NAFLD) encompasses a wide spectrum of liver pathologies. However, not medical treatment has been approved for the treatment of the disease. In our previous study, we found PKLR could be a potential target for treatment of NALFD. Here, the aim is to investigate the effect of PKLR in in vivo model and perform drug repositioning to identify a drug cand...

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Literature Corpus work: 5bc25d4f-9324-5916-ac67-65c7b9298e08
DOI: 10.1101/2022.02.15.480557

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