Article

Adolescent Triple-negative Breast Cancer with Germline Mutation of both BRCA1 and TP53: A Case Report

2022-06-03

Abstract excerpt

Almost 5–10% of breast cancer cases have inherited mutations. TP53 tumor suppressor gene is frequently mutated in human malignancies, including breast cancer. In addition, BRCA1 and BRCA 2 are the most frequently mutated genes in breast cancer. Nearly 80% of BRCA1 mutation carriers are diagnosed with breast cancer at a young age before menopause. There are currently no report of early onset breast cancer with both...

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Literature Corpus work: 5b51236f-538a-5cab-868c-703798097cd4
DOI: 10.21203/rs.3.rs-1680356/v1

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