Article

Palmitate-triggered COX2/PGE2-Mediated Hyperinflammation In Dual-stressed Pdl Fibroblasts Is Mediated by Repressive H3K27 Trimethylation

2022-01-21

Abstract excerpt

The interrelationship between periodontal disease, obesity-related hyperlipidemia and mechanical forces as well as their modulating effects on the epigenetic profile of periodontal ligament (PdL) cells are assumed to be remarkably complex. The PdL serves as connective tissue between teeth and alveolar bone for pathogen defense and inflammatory response to mechanical stimuli occurring during tooth movement. Altered...

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Literature Corpus work: 5b4b57fd-a8f6-5478-b955-e5ed7730facc
DOI: 10.20944/preprints202201.0321.v1

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