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Article

Characteristic phenotype of immortalized periodontal cells isolated from a Marfan syndrome type I patient.

Cell and tissue research - 1 Feb 2008

Shiga Momotoshi, Saito Masahiro, Hattori Mitsu, Torii Chiharu, Kosaki Kenjiro, Kiyono Tohru, Suda Naoto

Abstract excerpt

The periodontal ligament (PDL) is situated between the tooth root and alveolar bone, thereby supporting the tooth, and is composed of collagen and elastic system fibers. Marfan syndrome type I (MFS1, MIM #154700) is caused by mutations in FBN1 encoding fibrillin-1, which is a major microfibrillar protein of elastic system fibers. MFS1 is characterized by tall stature, aortic/mitral valve prolapse, and ectopia...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18049824
DOI: 10.1007/s00441-007-0528-x

Genes

FBN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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