Article

Temporal Control of Decidual Inflammation by HOXA10 is Essential for Implantation and its Dysregulation is Associated with Early Pregnancy Loss

2025-12-05

Abstract excerpt

Successful implantation requires precisely timed endometrial inflammation. Although an initial inflammatory burst is essential for implantation, this response must be rapidly resolved for placentation and pregnancy to progress. The mechanisms that coordinate this temporal switch remain poorly understood. Here, we identify the transcription factor HOXA10 as a key regulator of inflammatory transitions in decidual st...

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Literature Corpus work: 5adc70b3-4419-5268-af69-7529e8c45df8
DOI: 10.64898/2025.12.02.691844

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