Article

Single-cell profiling of human subventricular zone progenitors identifies SFRP1 as a target for stimulating progenitor activation

2021-10-26

Abstract excerpt

<title>Abstract</title> <p>Following the decline of neurogenesis at birth, progenitors of the subventricular zone (SVZ) remain mostly in a quiescent state in the adult human brain. The mechanisms that regulate this quiescent state are still unclear. Here, we isolated CD271+ progenitors from the aged human SVZ for single-cell RNA sequencing analysis. Our transcriptome data revealed the identity of progenitors of t...

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Literature Corpus work: 5a9d245c-6607-5f43-8f95-6957e63dea2c
DOI: 10.21203/rs.3.rs-151881/v1

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Single-cell profiling of human subventricular zone progenitors identifies SFRP1 as a target for stimulating progenitor activationDOI 10.21203/rs.3.rs-151881/v1Read

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