Article
A molecular toolbox for ADP-ribosyl binding proteins
2021-05-31
Abstract excerpt
Proteins interacting with ADP-ribosyl groups are often involved in disease-related pathways or in viral infections, which makes them attractive targets for the development of inhibitors. Our goal was to develop a robust and accessible assay technology that is suitable for high-throughput screening and applicable to a wide range of proteins acting as either hydrolysing or non-hydrolysing binders of mono- and poly-A...
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Identifiers and source
- Literature Corpus work
- 5a81d660-a0a8-56d7-a38e-c5cc27d6718f
- DOI
- 10.1101/2021.05.31.445082