Back to search

Article

HER2 expression in peritoneal dissemination of high-grade serous ovarian carcinoma: a comparative study of immunohistochemical reactivity using four HER2 antibodies

2022-11-28

Abstract excerpt

<title>Abstract</title> <p> <bold>Objective:</bold> Most high-grade serous ovarian carcinomas (HGSOCs) involving the peritoneum are highly aggressive. Epidermal growth factor receptor 2 (HER2) is aberrantly activated and a therapeutic target in a variety of solid cancers. However, the role of HER2 in HGSOC is still controversial. The HER2 status of a tumor is based on cytoplasmic membrane staining of an intrace...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
5a5f9011-e43a-51d7-bf11-f372d1d2ac4e
DOI
10.21203/rs.3.rs-1690181/v2
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 8 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
HER2 expression in peritoneal dissemination of high-grade serous ovarian carcinoma: a comparative study of immunohistochemical reactivity using four HER2 antibodiesDOI 10.21203/rs.3.rs-1690181/v2
Estrogen receptor and progesterone receptor status and their prognostic implications in pelvic high-grade serous carcinomas: A retrospective studySemantic proximity
Molecular similarities between primary peritoneal and primary ovarian carcinomas.Semantic proximity
Primary peritoneal serous papillary carcinoma: a new epidemiologic trend? A matched-case comparison with ovarian serous papillary cancer.Semantic proximity
Gene amplification, mutation, and protein expression of EGFR and mutations of ERBB2 in serous ovarian carcinoma.Semantic proximity
HER2 amplification and overexpression are significantly correlated in mucinous epithelial ovarian cancerSemantic proximity
Overview of Tumor Heterogeneity in High-Grade Serous Ovarian Cancers.Semantic proximity
Homologous recombination deficiency and Cyclin E1 amplification are correlated with immune cell infiltration and survival in high-grade serous ovarian cancer.Semantic proximity
Peritoneal dissemination of high-grade serous ovarian cancer: pivotal roles of chromosomal instability and epigenetic dynamicsSemantic proximity
Select a neighboring publication to make it the new centre.