Article
Gut DNA Virome Diversity and Its Association with Host Bacteria Regulate Inflammatory Phenotype and Neuronal Immunotoxicity in Experimental Gulf War Illness.
Viruses - 21 Oct 2019
Seth Ratanesh K, Maqsood Rabia, Mondal Ayan, Bose Dipro, Kimono Diana, Holland LaRinda A, Janulewicz Lloyd Patricia, Klimas Nancy, Horner Ronnie D, Sullivan Kimberly, Lim Efrem S, Chatterjee Saurabh
Abstract excerpt
Gulf War illness (GWI) is characterized by the persistence of inflammatory bowel disease, chronic fatigue, neuroinflammation, headache, cognitive impairment, and other medically unexplained conditions. Results using a murine model show that enteric viral populations especially bacteriophages were altered in GWI. The increased viral richness and alpha diversity correlated positively with gut bacterial dysbiosis...
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