Gonadotropin and kisspeptin receptor function in granulosa cells from women with and without Polycystic Ovary Syndrome

Abstract excerpt

Polycystic ovary syndrome (PCOS) is a common, complex and heterogenous condition which affects 8-13% of women. The underlying aetiology is poorly understood and evidence suggests that it is multigenic disorder with strong epigenetic and environmental influences. Recent genome wide association studies have found hits close to loci encoding FSHR and LHCGR, implicating gonadotropin receptor action in the pathogenesis...

Topics

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• Gene Expression
• Hypothalamic control of reproductive hormones
• Mutation
• Ovary
• Receptors, FSH
• Receptors, LH
• Receptors, Prolactin
• Reproductive Biology and Fertility

Identifiers and source

Literature Corpus work

5a222b93-af8a-5b5c-98e9-1ccb1f99c18c

DOI

10.25560/73869