Article

Genetic aetiologies for childhood speech disorder: novel pathways co-expressed during brain development

2022-05-16

Abstract excerpt

Childhood apraxia of speech (CAS), the prototypic severe childhood speech disorder, is characterized by motor programming and planning deficits. Genetic factors make substantive contributions to CAS aetiology, with a monogenic pathogenic variant identified in a third of cases, implicating around 20 single genes to date. Here we ascertained 70 unrelated probands with a clinical diagnosis of CAS and performed trio g...

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Literature Corpus work: 59fb2e7a-ff46-5738-b1f8-9b5bd04e4dcc
DOI: 10.1101/2022.05.15.22274630

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