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Article

The clinical and genetic spectrum of paediatric speech and language disorders.

Brain : a journal of neurology - 3 Feb 2025

Magielski Jan H, Ruggiero Sarah M, Xian Julie, Parthasarathy Shridhar, Galer Peter D, Ganesan Shiva, Back Amanda, McKee Jillian L, McSalley Ian, Gonzalez Alexander K, Morgan Angela, Donaher Joseph, Helbig Ingo

Abstract excerpt

Speech and language disorders are known to have a substantial genetic contribution. Although frequently examined as components of other conditions, research on the genetic basis of linguistic differences as separate phenotypic subgroups has been limited so far. Here, we performed an in-depth characterization of speech and language disorders in 52 143 individuals, reconstructing clinical histories using a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39412438
DOI: 10.1093/brain/awae264
PMCID: PMC11788197

Genes

STXBP1
BCHE
CACNA1A
KIF17
MYO7A
PTEN
SLC22A9
UMODL1
UQCRC1
USP37

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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