Article

Predicting drug targets by homology modelling of <i>Pseudomonas aeruginosa</i> proteins of unknown function

2021-06-15

Abstract excerpt

Efficacies of antibiotics to treat bacterial infections rapidly decline due to antibiotic resistance. This stimulated the development of novel antibiotics, but most attempts failed. As a response, the idea of mining uncharacterised genes of pathogens to identify potential targets for entirely new classes of antibiotics raised. Without knowing the biochemical function of a protein it is difficult to validate its po...

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Literature Corpus work: 59f884ed-1b07-594b-aecb-785abf1139a4
DOI: 10.1101/2021.06.15.448521

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