Article

From Sound Abduction to Governed Intervention: A Closed-Loop Architecture for Medical Digital Twins in Multiple Sclerosis Care

2026-07-31

Abstract excerpt

Medical digital twins are increasingly presented as dynamic computational representations that integrate longitudinal clinical, imaging, biological, behavioural, and patient-generated data. Yet a central problem remains unresolved: how should an explanatory inference be translated into a clinically permissible intervention? This paper proposes a governed closed-loop architecture for digital twins in multiple scler...

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Literature Corpus work: 59dc5252-1bd4-5236-96a1-5b1b9ecd74f9
DOI: 10.20944/preprints202607.2365.v1

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