Article

From Plausible Narrative to Sound Abduction: A Governed Abductive Architecture for Medical Digital Twins in Multiple Sclerosis Care

2026-05-12

Abstract excerpt

Large language models (LLMs) embedded in medical Patient Digital Twins (PDTs) exhibit a systemic vulnerability: they can generate fluent, narratively persuasive, yet abductively unsound clinical explanations. In this context, abductive soundness means that an explanation preserves mechanistic plausibility, temporal coherence, explicit handling of missing premises, and sensitivity to counter-evidence. This article...

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Literature Corpus work: d6a1928d-ab81-55b2-b964-f1477109556f
DOI: 10.20944/preprints202605.0728.v1

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