Back to search

Article

New perspective: the multi-targets mechanism of hydroxychloroquine in the treatment of rheumatoid arthritis based on network pharmacology

2020-08-28

Abstract excerpt

<title>Abstract</title> <p>Background Network pharmacology is a new method of bioinformatics in exploring drug targets in recent 3 years. Hydroxychloroquine (HCQ) is a multi-targets drug that are clinically effective in rheumatoid arthritis (RA) but whose mechanism is not well understood. Methods The predicted targets of HCQ and the proteins related to RA were returned from databases. Followed by protein-protei...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
59290777-1e60-5fae-a0be-4a6836af7d7b
DOI
10.21203/rs.3.rs-65359/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
New perspective: the multi-targets mechanism of hydroxychloroquine in the treatment of rheumatoid arthritis based on network pharmacologyDOI 10.21203/rs.3.rs-65359/v1
The multi-targets mechanism of hydroxychloroquine in the treatment of systemic lupus erythematosus based on network pharmacologySemantic proximity
Network pharmacological analysis of hydroxychloroquine intervention in the treatment of IgA NephropathySemantic proximity
Network pharmacology and molecular docking to elucidate the common mechanism of hydroxychloroquine treatment in lupus nephritis and IgA nephropathySemantic proximity
Integrative Multi-Omics and In Silico Computational Analysis Revealed, Marine-Derived Compounds as Potential Therapeutics Targeting Key Regulatory Genes in Rheumatoid ArthritisSemantic proximity
Network Analysis Indicating the Pharmacological Mechanism of Yunpi-Qufeng- Chushi-Prescription in Prophylactic Treatment of Rheumatoid ArthritisSemantic proximity
Bioinformatics Analysis Screened and Identified Key Genes, miRNAs and TFs as Potential Biomarkers for Progression of Rheumatoid ArthritisSemantic proximity
A network-based model for drug repurposing in Rheumatoid ArthritisSemantic proximity
Bioinformatics Identification of Ferroptosis-related Genes and Therapeutic Drugs in Rheumatoid ArthritisSemantic proximity
Detecting potential mechanism of vitamin D in treating rheumatoid arthritis based on network pharmacology and molecular dockingSemantic proximity
The Mechanism of Rose in Treating Sjögren's Syndrome Based on Network Pharmacology and Molecular DockingSemantic proximity
Identification of Potential Therapeutic Targets For Rheumatoid Arthritis By BioinformaticsSemantic proximity
Network pharmacology and in silico approaches to uncover multitargeted mechanism of action of Zingiber zerumbet rhizomes for the treatment of idiopathic pulmonary fibrosisSemantic proximity
Select a neighboring publication to make it the new centre.