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Article

The multi-targets mechanism of hydroxychloroquine in the treatment of systemic lupus erythematosus based on network pharmacology

27 Aug 2020

Abstract excerpt

BACKGROUND: Network pharmacology is used with bioinformatic tools to broaden the understanding of drugs' potential targets and the intersections with key genes of particular disease. Here we applied network pharmacology to collect testable hypotheses about the multi-targets mechanism of hydroxychloroquine (HCQ) against systemic lupus erythematosus (SLE). METHODS: Firstly, we predicted the potential targets of...

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PMID: 32854577
DOI: 10.1177/0961203320952541

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