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A novel S100A-TLR3-IFIT3 signaling axis promotes cardiomyocyte apoptosis during myocardial infarction

2026-03-08

Abstract excerpt

<title>Abstract</title> <p>Ischemic cardiomyopathy is associated with myocardial injury and increased mortality. During myocardial infarction (MI), necrotic cardiomyocytes release damage-associated molecular patterns (DAMPs) that trigger inflammatory responses, yet the specific cardiac alarmins and downstream mechanisms driving cardiomyocyte apoptosis remain unclear. In this study, we identified endogenous S100 p...

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Literature Corpus work
58cdc53b-7512-5a1f-ab61-1213c06c0bf9
DOI
10.21203/rs.3.rs-8733111/v1
Open publication

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A novel S100A-TLR3-IFIT3 signaling axis promotes cardiomyocyte apoptosis during myocardial infarctionDOI 10.21203/rs.3.rs-8733111/v1
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