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Multi-Center Study of Resectable Lung Lesions by Ultra-Deep Sequencing of Targeted Genes in Plasma Cell-Free DNA to Assess Nodule Malignancy and Detect Lung Cancers

2018-10-26

Abstract excerpt

<h4>BACKGROUND</h4> Early detection of lung cancer to allow curative treatment remains challenging. Cell-free circulating tumor DNA (ctDNA) analysis may aid in malignancy assessment and early cancer diagnosis of lung nodules found in screening imagery. <h4>METHODS</h4> The multi-center clinical study enrolled 192 patients with operable occupying lung diseases. Plasma ctDNA, white blood cell genomic DNA (gDNA) an...

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Literature Corpus work: 58ae62e4-8a44-5b6a-b5e5-04f50103a3d6
DOI: 10.1101/453803

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