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Article

<i>Ex vivo</i> drug testing in an ultra-rare sarcoma reveals therapeutic vulnerability and resistance

2022-08-04

Abstract excerpt

<h4>ABSTRACT</h4> Solitary fibrous tumors (SFTs) are rare soft tissue sarcomas for which therapeutic options are limited and ineffective. We successfully demonstrated how functional personalized treatment was implemented in the clinic for an ultra-rare sarcoma with otherwise limited options, through a combined strategy of patient-derived model development and computational drug analytics. Molecular profiling of tu...

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Literature Corpus work
58a457cd-31af-5e2c-a564-616cbe0cccae
DOI
10.1101/2022.08.03.22278327
Open publication

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<i>Ex vivo</i> drug testing in an ultra-rare sarcoma reveals therapeutic vulnerability and resistanceDOI 10.1101/2022.08.03.22278327
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