Article
A Functional Precision Oncology Approach to Identify Treatment Strategies for Myxofibrosarcoma Patients.
Molecular cancer research : MCR - 1 Feb 2022
Pauli Chantal, De Boni Lamberto, Pauwels Jonathan E, Chen Yanjiang, Planas-Paz Lara, Shaw Reid, Emerling Brooke M, Grandori Carla, Hopkins Benjamin D, Rubin Mark A
Abstract excerpt
In this era of precision medicine, numerous workflows for the targeting of high-recurrent mutations in common tumor types have been developed, leaving patients with rare diseases with few options. Here, we implement a functional precision oncology approach utilizing comprehensive genomic profiling in combination with high-throughput drug screening, to identify tumor-specific drug sensitivities for patients with...
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