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MSGPCA: Multi-Slice Graph PCA for replicate-aware Spatial Omics analysis

2026-08-11

Abstract excerpt

As spatial transcriptomics (ST) and spatial proteomics (SP) technologies mature, experimental designs are increasingly moving beyond single-slice analyses toward multi-slice studies involving one or more donors and experimental conditions. Although these designs enable the identification of reproducible spatial signals, they also introduce substantial biological heterogeneity, particularly when integrating non-ser...

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Literature Corpus work
58a232e9-35eb-57df-adca-be9595c8640d
DOI
10.64898/2026.08.05.743056
Open publication

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MSGPCA: Multi-Slice Graph PCA for replicate-aware Spatial Omics analysisDOI 10.64898/2026.08.05.743056
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