Article

Contrasting Sequence with Structure: Pre-training Graph Representations with PLMs

2023-12-04

Abstract excerpt

Understanding protein function is vital for drug discovery, disease diagnosis, and protein engineering. While Protein Language Models (PLMs) pre-trained on vast protein sequence datasets have achieved remarkable success, equivalent Protein Structure Models (PSMs) remain underrepresented. We attribute this to the relative lack of high-confidence structural data and suitable pre-training objectives. In this context,...

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Literature Corpus work: 588ab370-3522-5341-b4c0-c38aabceb544
DOI: 10.1101/2023.12.01.569611

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