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TRAF3 Suppression Encourages B Cell Recruitment and Prolongs Survival of Microbiome-Intact Mice with Ovarian Cancer

2023-02-09

Abstract excerpt

<h4>Background</h4> Ovarian cancer (OC) has proven to be the most deadly of all gynecologic cancers. Clinical trials involving the use of immunotherapies in OC patients have produced disappointing outcomes, underscoring the necessity of identifying new immunomodulatory targets for the treatment of this cancer. <h4>Methods</h4> We conducted an in-vivo CRISPR screen of immunodeficient (NSG) and immune-intact wild...

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Literature Corpus work
5878eeab-98d7-566b-9ce3-ae3b3340f301
DOI
10.1101/2023.02.09.527814
Open publication

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TRAF3 Suppression Encourages B Cell Recruitment and Prolongs Survival of Microbiome-Intact Mice with Ovarian CancerDOI 10.1101/2023.02.09.527814
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