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Inflammation and Immune Escape in Ovarian Cancer: Pathways and Therapeutic Opportunities

1 Jan 2025

Abstract excerpt

Ovarian cancer (OC) remains one of the most lethal gynecological malignancies, largely due to its late-stage diagnosis and high recurrence rates. Chronic inflammation is a critical driver of OC progression, contributing to immune evasion, tumor growth, and metastasis. Inflammatory cytokines, including IL-6, TNF-α, and IL-8, as well as key signaling pathways such as nuclear factor kappa B (NF-kB) and signal...

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PMID: 39867950
DOI: 10.2147/jir.s503479

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