Article

Initiation of human cytomegalovirus secondary envelopment requires the gM/gN glycoprotein complex and involves palmitoylation

2025-09-16

Abstract excerpt

<h4>ABSTRACT</h4> Glycoprotein M (gM) of human cytomegalovirus (HCMV) forms a protein complex with glycoprotein N (gN), whose precise function in viral morphogenesis is poorly understood. Both proteins are highly conserved across herpesviruses and likely perform similar functions in virion assembly and egress, with the gM/gN complex being essential for HCMV morphogenesis. To elucidate the function of the gM/gN co...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 581a48e9-6f9d-5b1c-9fd7-ef0e4cac4f77
DOI: 10.1101/2025.09.16.676473

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Initiation of human cytomegalovirus secondary envelopment requires the gM/gN glycoprotein complex and involves palmitoylationDOI 10.1101/2025.09.16.676473Read

Initiation of human cytomegalovirus secondary envelopment requires the gM/gN glycoprotein complex and involves palmitoylation.Semantic proximity Read

The carboxy-terminal domain of glycoprotein N of human cytomegalovirus is required for virion morphogenesis.Semantic proximity Read

The cytoplasmic tail of glycoprotein M (gpUL100) expresses trafficking signals required for human cytomegalovirus assembly and replication.Semantic proximity Read

Glycoprotein M is important for the efficient incorporation of glycoprotein H–L into herpes simplex virus type 1 particlesSemantic proximity Read

Regulation of Human Cytomegalovirus Secondary Envelopment by a C-Terminal Tetralysine Motif in pUL71Semantic proximity Read

Complex Formation by Glycoproteins M and N of Human Cytomegalovirus: Structural and Functional AspectsSemantic proximity Read

A Tyrosine-Based Trafficking Motif of the Tegument Protein pUL71 Is Crucial for Human Cytomegalovirus Secondary Envelopment.Semantic proximity Read

An acidic cluster of human cytomegalovirus UL99 tegument protein is required for trafficking and function.Semantic proximity Read

The Human Cytomegalovirus (HCMV) Tegument Protein UL94 Is Essential for Secondary Envelopment of HCMV VirionsSemantic proximity Read

Human Cytomegalovirus UL99-Encoded pp28 Is Required for the Cytoplasmic Envelopment of Tegument-Associated CapsidsSemantic proximity Read

Analysis of human cytomegalovirus secondary envelopment by advanced electron microscopy.Semantic proximity Read

The Tegument Protein UL71 of Human Cytomegalovirus Is Involved in Late Envelopment and Affects Multivesicular BodiesSemantic proximity Read