LAMP-coupled CRISPR-Cas12a assays for upgrading molecular detection of <i>Leishmania</i> infections

Abstract excerpt

<h4>Background</h4> Tegumentary leishmaniasis is a parasitic disease endemic in the Americas. Its clinical management and control rely on early and accurate diagnosis and adequate treatment. PCR-based molecular diagnostics offer high sensitivity and specificity over microscopy or culture but are less accessible in low-resource settings. New molecular tools for detecting Leishmania infections are needed in rural e...

Topics

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• CRISPR and Genetic Engineering
• Cytomegalovirus and herpesvirus research
• Innovation and Socioeconomic Development
• Leptospirosis research and findings
• Malaria Research and Control
• Mosquito-borne diseases and control
• Research on Leishmaniasis Studies
• Toxoplasma gondii Research Studies

Identifiers and source

Literature Corpus work

57e957eb-8e0b-50f0-bbfb-22868f33f489

DOI

10.1101/2025.08.08.25333281