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Article

Pathogenesis of glucocorticoid-induced avascular necrosis: A microarray analysis of gene expression in vitro

6 Jul 2015

Abstract excerpt

Avascular necrosis of the femoral head (ANFH) occurs following exposure to corticosteroids, and the proliferative capacity of the mesenchymal stem cells (MSCs) belonging to ANFH was reduced. The previous studies indicate that microRNA (miRNA) has an important regulatory role during proliferation and osteogenic differentiation of MSCs. Therefore, MSCs were obtained from healthy adults, and were cultured and...

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PMID: 26151338
DOI: 10.3892/ijmm.2015.2273

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