Article

A spatial statistical framework for the parametric study of fiber networks: application to fibronectin deposition by normal and activated fibroblasts

2022-06-16

Abstract excerpt

Changes in the spatial landscape of the extracellular matrix (ECM) in health and disease significantly impact the surrounding tissues. Quantifying the spatial variations in the fibrillar architecture of major ECM proteins could enable a profound understanding of the link between tissue structure and function. We propose a method to capture relevant ECM features using graph networks for fiber representation in norm...

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Literature Corpus work: 576640d5-489c-540a-8459-9bde13edb091
DOI: 10.1101/2022.06.14.496046

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